Hallux Mobilization in Patients With Parkinson's Disease (HalluxPD001)

Ospedale Generale Di Zona Moriggia-Pelascini

Status: Completed

Conditions: Parkinson Disease

Treatments: Other: MIRT; Other: Mobilization of the metatarsophalangeal joint of the hallux

Study type: Observational

Funder types: Other

Identifiers

NCT02098642

Hallux PD 001 (Other Identifier)

HalluxPD001

Details and patient eligibility

About

Parkinson's disease is a degenerative disorder of the central nervous system. The motor symptoms of Parkinson's disease result from the death of dopamine-generating cells in the substantia nigra, a region of the midbrain; the cause of this cell death is unknown. Early in the course of the disease, the most obvious symptoms are movement-related; these include shaking, rigidity, slowness of movement and difficulty with walking and gait. A multidisciplinary intensive rehabilitation treatment (MIRT) is able to improve different parameters in PD that are poorly responsive to dopaminergic therapy. In this study, we aim to understand whether the passive mobilization of the metatarsophalangeal joint of the hallux determines an increase in the joint range in this district, allowing to improve, at least, the gait.

Full description

Parkinson's disease is a degenerative disorder of the central nervous system. The motor symptoms of Parkinson's disease result from the death of dopamine-generating cells in the substantia nigra, a region of the midbrain; the cause of this cell death is unknown. Early in the course of the disease, the most obvious symptoms are movement-related; these include shaking, rigidity, slowness of movement and difficulty with walking and gait. The main families of drugs useful for treating motor symptoms are levodopa dopamine agonists and Monoamine oxidases-B inhibitors.A multidisciplinary intensive rehabilitation treatment (MIRT) is able to improve different parameters in PD that are poorly responsive to the pharmacological therapy. In this study, we aim to understand whether the passive mobilization of the metatarsophalangeal joint of the hallux determines an increase in the joint range in this district, allowing to improve, at least, the gait in patients with PD. In this course, we will evaluate whether passive mobilization of this joint, lead to positive effects on the freezing of gait and on the festination.

Enrollment: 100 patients

Sex: All

Ages: 49 to 88 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

PD patients stage 3 H&Y with FOG

Exclusion criteria

we excluded patients with atypical parkinsonism, with other concomitant neurological conditions (with cerebrovascular etc.), with joint disorders, muscle disorders or with other orthopedic conditions.

Trial design

100 participants in 2 patient groups

Patients with passive joint mobilization

Description:

Patients diagnosed with PD according to the Gelb et al in Hoen\&Yahr stage 3, with Freezing of Gait and treated with a Multidisciplinary intensive rehabilitation treatment (MIRT), including the mobilization of the metatarsophalangeal joint of the hallux

Treatment:

Other: MIRT

Other: Mobilization of the metatarsophalangeal joint of the hallux

No passive joint mobilization

Description:

Patients diagnosed with PD according to the Gelb et al in Hoen\&Yahr stage 3, with Freezing of Gait and treated with a Multidisciplinary intensive rehabilitation treatment (MIRT)

Treatment:

Other: MIRT