Hämeenlinna Metabolic Syndrome Research Program: Effects of Rapeseed Oil on Serum Lipids and Platelet Function (HMS-03)

Kanta-Häme Central Hospital

Status: Completed

Conditions: Metabolic Syndrome

Treatments: Dietary Supplement: Cold-pressed turnip rapeseed oil (CTPRO); Dietary Supplement: milk fat

Study type: Interventional

Funder types: Other

Identifiers

NCT01119690

KHMetS-03-AP

HMS-03 (Other Identifier)

Details and patient eligibility

About

In this study, the effects of dietary intake of cold-pressed turnip rapeseed oil (CTPRO) and milk fat are compared in men with metabolic syndrome having already participated in HMS-02 study.

Full description

This open and balanced cross-over study consists of two dietary treatment phases (either Virgino (R) CTPRO or butter) for 6 to 8 weeks. They are separated from each other with an eight-week washout period. At the end of both periods and 12-hour fasting an oral glucose-fat tolerance test is carried out. Except glucose, the test consists cream (after the butter phase) and CTPRO (after the CTPRO phase).

Otherwise, the subjects (n=43) are asked to maintain their normal dietary habits.

Enrollment: 43 patients

Sex: Male

Ages: 31 to 66 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• 43 men with metabolic syndrome having already participated in the HMS-02 Study
• Willing to participate in a demanding dietary study

Exclusion Criteria:

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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43 participants in 2 patient groups

Rapeseed oil

Active Comparator group

Treatment:

Dietary Supplement: Cold-pressed turnip rapeseed oil (CTPRO)

Milk fat

Active Comparator group

Treatment:

Dietary Supplement: milk fat