Hard and Soft Tissue Dimensional Change After Consecutive Extractions and Unassisted Socket Healing in the Esthetic Zone

Shanghai Jiao Tong University

Status: Not yet enrolling

Conditions: Wound Heal

Study type: Observational

Funder types: Other

Identifiers

NCT06261762

SDC-24-1

Details and patient eligibility

About

The goal of this observational study is to evaluate the post-extraction hard and soft tissue dimension changes in patients requiring consecutive extractions and unassisted socket healing in the anterior maxilla. The main questions it aims to answer are:

• Is significant alveolar ridge resorption observed at center sites after consecutive extractions
• Is significant alveolar ridge resorption observed at the interalveolar septum after consecutive extractions, are different extraction sites associated with significantly different bone resorption
• Is a thick or thin wall phenotype associated with the amount of bone resorption
• Is soft tissue thickness change associated with the corresponding location (extraction site or interalveolar septum) and post-extraction thickness of the bone
• Is the interdental papilla height significantly affected after extractions.

Participants will undergo consecutive (two) extractions and will be evaluated after subsequent unassisted socket healing for 8 weeks.

Enrollment: 20 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18+ years old
• Require consecutive (two) teeth replacement in the anterior maxilla
• Signed informed consent
• No significant medical conditions
• Patients with healthy periodontal conditions or previously treated to controlled and stable conditions

Exclusion criteria

• General medical (American Society of Anesthesiologists, ASA, class III or IV) and/or psychiatric contraindications
• Pregnancy or nursing
• Any interfering medication such as steroid therapy or bisphosphonate therapy
• Uncontrolled diabetes
• Autoimmune diseases or inflammatory diseases affecting the intraoral tissues
• Radiation therapy to head or neck region