Harmonized and Pooled Database, Named PRIME.

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Status: Completed

Conditions: Invasive Ventilation

Treatments: Other: Invasive ventilation

Study type: Observational

Funder types: Other

Identifiers

NCT06592937

PRIME-NEU

Details and patient eligibility

About

We merged the dataset of three large observational studies of invasive ventilation in critically ill patients.

Full description

PRIME contains the individual patient data of 3 large observational studies of ventilation, 'PRactice of VENTilation in critically ill patients without ARDS' (PRoVENT), 'PRactice of VENTilation in critically ill patients in Middle-income Countries' (PRoVENT-iMiC) and 'Extubation strategies and in neuro-intensive care unit patients and associations with outcomes' (ENIO).

Enrollment: 3,270 patients

Sex: All

Ages: 18 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

All patients in the PRIME database are eligible for participation in the initial analysis presented here. We will exclude patients receiving ventilation fir another reason than acute brain injury.

Trial design

3,270 participants in 1 patient group

Patients receiving invasive ventilation

Description:

Patients receiving invasive ventilation, included in PRoVENT, PRoVENT-iMiC, and ENIO

Treatment:

Other: Invasive ventilation