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The goal of this study is to evaluate the role of transcription factor EB (TFEB) in adipose (fat) tissue macrophages (ATM) in regulating adipose tissue and systemic metabolic function in obesity. The investigators will assess the differences in ATM lipid metabolism in people with metabolically abnormal obesity and lean individuals.
Both groups will have:
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Inclusion and exclusion criteria
Inclusion Criteria :
Lean group:
Metabolically normal obesity (MNO) group:
Metabolically abnormal obesity (MAO)-insulin resistance and non-alcoholic fatty liver disease (NAFLD) group:
MAO-type 2 diabetes group:
Exclusion Criteria:
60 participants in 4 patient groups
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Central trial contact
Aman Pritish Aher; Heather McHatton
Data sourced from clinicaltrials.gov
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