Have a Good Grasp of the Worldthe World (GRASP)

Centre Hospitalier Universitaire de Saint Etienne

Status

Completed

Conditions

Schizophrenic Disorders

Treatments

Other: cognitive tasks + PANSS+ IQ

Other: cognitive tasks

Study type

Interventional

Funder types

Other

Identifiers

NCT02655172

2015-A01939-40 (Other Identifier)

1508205

Details and patient eligibility

About

Brief Summary: In schizophrenia, dislocation of psychic functions involving a loss of contact with reality is frequently found. A fragmentation of motor and sensory perceptions could be held responsible. However, automatic integration between perception and action is the necessary condition to be in "relationship with the world." Affordance is the experimental link between object perception and potentially associated actions (Gibson, 1977, 1979) explored by Stimulus Response Compatibility (SRC) paradigm. With Tucker & Ellis sensory motor compatibility task (1998), with a modified response device (responses given with grasp), we study the impact of motor activation on these affordance effects. In this study, a group of controls will also be included in order to understand, as precisely as possible, the mechanisms involved (i.e., interference between the perception of the object and the response gesture).

Full description

Schizophrenic patients will perform: Alert TEA, (Zimmermann and Fimm, 2005), Edinburgh laterality questionnaire (Oldfield, 1971), IQ test (IQ: PM38, Raven, 1960), and the PANSS (Positive and Negative Syndrome Scale, Kay et al., 1987). Controls will only perform the laterality questionnaire. Then all will perform the affordance task, in which photographs of 20 objects of everyday life, typically graspable with one hand, are presented in 4 orientations. Participants have to respond in a graspable device, as quickly as possible, if the object is presented upright or inverted.

Enrollment

41 patients

Sex

All

Ages

18 to 55 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

For patients:
- a DSM-IV diagnosis of schizophrenia (men or women),
- no change in antipsychotic medication and clinical status within four weeks prior to the study
For patients and control group • Age ≥ 18 years et ≤ 55 years

Exclusion criteria

History of head trauma,
neurological disease with cerebral repercussion or not stabilized serious physical illness;
psychotropic medication
disorders related to the use of a psychoactive substance (abuse, dependence or withdrawal);

Exclusion Criteria:

For patients:

• IQ < 70
For patients and control group
- History of head trauma,
- neurological disease with cerebral repercussion or not stabilized serious physical illness;
- psychotropic medication
- disorders related to the use of a psychoactive substance (abuse, dependence or withdrawal);