Healing Assessment of Osseous Defects After Surgical Removal of Periapical Lesions

Minia University

Status: Unknown

Conditions: Effects of the Elements

Treatments: Procedure: surgery

Study type: Interventional

Funder types: Other

Identifiers

NCT05100615

238

Details and patient eligibility

About

recruited patients with periapical lesions will be divided into three groups and surgically treated with three types of bone graft (hydroxyappatite, nanohydroxyappatite and PRF WITH NANOHYDROXTAPPATITE) and then evaluated for month, three months and six months for the healing of periapical bone

Enrollment: 24 estimated patients

Sex: All

Ages: 20 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• The patient will be in range of 20-45 years of age at the time of treatment, having periapical lesions starting from 5mm or more in diameter related to failed endodontically treated single canaled teeth.

Exclusion criteria

• Any systemic debilitating disease such as:

Diabetes mellitus, renal disease, Liver disease or liver failure, Rheumatoid arthritis, Neoplastic disease or its treatment, chronic corticosteroid therapy, chronic hepatitis B or C , History of hepatitis A, pregnant females.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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24 participants in 3 patient groups

hydroxyappatite

Other group

Description:

hydroxyapatite powder used for enhancement of bone regeneration

Treatment:

Procedure: surgery

nanohydroxyapatite

Other group

Description:

nanohydroxyapatite powder used for enhancement of bone regeneration

Treatment:

Procedure: surgery

PRF with nanohydroxyapatite

Other group

Description:

platelet rich fibrin mixed with nanohydroxyapatite used for enhancement of bone regeneration

Treatment:

Procedure: surgery