Healing Effect of Tea Tree Oil on Burn

Alexandria University

Status and phase: Completed; Early Phase 1

Conditions: Burn

Treatments: Drug: tea tree oil ointment

Study type: Interventional

Funder types: Other

Identifiers

NCT07149844

1482025

Details and patient eligibility

About

Tea tree oil (TTO) has been recognized for its effectiveness in treating infected burns, insect bites, and promoting wound healing. This clinical study aimed to compare the impact of Tea tree oil dressings versus conventional ones in the healing process of second degree burns wounds.

Full description

This quasi-experimental comparative controlled clinical trial was conducted at the Burn Unit of Ras-Elteen General Hospital in Alexandria, Egypt. A purposive sample of 30 adult patients with second-degree burns on the chest, abdomen, upper limbs (excluding hands), and lower limbs (excluding feet) was enrolled from the Emergency and Outpatient Departments. Participants were sequentially assigned to two equal groups:

Control group (n=15): Received conventional dressings (sterile gauze with silver sulfadiazine).

Study group (n=15): Received topical 10% tea tree oil (TTO) ointment applied directly to wounds.Wounds were cleansed with sterile normal saline (0.9%), and non-viable tissue was debrided.

Dressings were changed every other day unless soiled or damp. Burns near joints were maintained in functional positions.Wound assessment was performed on days 7, 14, and 21 post-treatment

Enrollment: 30 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient willing to participate and communicate
• Newly admitted with recent 2nd-degree burns (superficial or deep) involving ≤10% of TBSA
• Length of hospital stay of 10 days

Exclusion criteria

Any associated illnesses that may affect wound healing, such as:

• Diabetes mellitus (DM)
• Immune disorders
• Pre-existing skin conditions (e.g., eczema)

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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30 participants in 1 patient group

conventional dressing

Other group

Description:

Conventional dressing: Is the routine study hospital's burn dressing technique, utilizing sterile topical gauze dressing that is impregnated with or laid over a topical antibacterial, silver sulphadiazin dressing secured with adhesive tape.

Treatment:

Drug: tea tree oil ointment