Health Benefits of Air Purifiers in Primary School Students

Fudan University

Status: Active, not recruiting

Conditions: Cardiopulmonary Function; Child

Treatments: Behavioral: Air purifier and fresh air ventilation systems with high-efficiency particulate air (HEPA) filters; Behavioral: Air purifier and fresh air ventilation systems without high-efficiency particulate air (HEPA) filters

Study type: Interventional

Funder types: Other

Identifiers

NCT05016271

FDUEH-7

Details and patient eligibility

About

This study aims to explore changes in cardiopulmonary function and other health indicators in primary school students with the intervention of air purifiers on a randomized controlled trial.

Full description

The investigators will conduct a randomized controlled trial among 110 healthy children in Jiaozuo city, Henan, China. The eligible children will be divided into two groups according to their classes and randomly receive interventions of either true or sham air purifiers. The air purifiers devices in classroom [air purifiers and fresh air ventilation systems] will operate during the school time and the devices in bedrooms (air purifiers) operate during the home time in the intervention period. All the participants and investigators will be blinded to the group assignment. Epidemiological questionnaires (i.e., basic characteristics, eating habits, daily schedule, etc.) will be conducted and health indicators (i.e., blood pressure, pulmonary function indicators, fractional exhaled nitric oxide, and fractional exhaled carbon monoxide) and biological specimens (i.e., morning urine, venous blood, exhaled breath condensate, and feces) will be evaluated and collected at baseline and after the completion of intervention period (4 months anticipated).

Enrollment: 110 estimated patients

Sex: All

Ages: 8 to 12 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age of between 8 and 12 years old
• Males and female of ethnic Han
• Subjects who have no plans to change classroom during the intervention period
• Subjects who staying in Jiaozuo city during the intervention period

Exclusion criteria

• Subjects with asthma, childhood diabetes, childhood hypertension, and behavioral disorders
• Subjects who plan to transfer or move offsite within six months
• Subjects who decorated or plan to decorate home within six months
• Subjects with smokers in the household

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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110 participants in 2 patient groups

True air purifier group

Experimental group

Description:

Children in this group will receive an intervention of air purifiers with high-efficiency particulate air (HEPA) filters.

Treatment:

Behavioral: Air purifier and fresh air ventilation systems with high-efficiency particulate air (HEPA) filters

Sham air purifier group

Sham Comparator group

Description:

Children in this group will receive an intervention of air purifiers without high-efficiency particulate air (HEPA) filters.

Treatment:

Behavioral: Air purifier and fresh air ventilation systems without high-efficiency particulate air (HEPA) filters