Health Benefits of Chronic vs. Acute Exercise in Overweight Adults

University of Michigan

Status: Completed

Conditions: Obesity

Treatments: Other: Exercise

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT01452087

R01 DK077966 - R

R01DK077966 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

Compare the effects of single session of exercise vs. chronic exercise training on key risk factors associated with Metabolic Syndrome (e.g., glucose tolerance, blood lipid profile, and blood pressure) in overweight adults.

Enrollment: 43 patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Body Mass Index: 27-34 kg/m2;
• Regular exercisers(≥4 days/wk of aerobic exercise;
• 30-60min/session at moderate and vigorous intensities);
• Non-exercisers (no regularly planned exercise/physical activity);
• Women must have regularly occurring menses and must be premenopausal.

Exclusion criteria

• Pregnant or lactating;
• Evidence/history of cardiovascular or metabolic disease;
• Currently taking medications known to affect lipid or glucose metabolism.

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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43 participants in 1 patient group

Exercise Session

Other group

Description:

Subjects will exercise on a treadmill for 1 hour at moderate intensity (i.e., 90% of the exercise intensity found to elicit their ventilatory threshold during the preliminary testing, which is equivalent to approximately 60% of their maximal predicted heart rate).

Treatment:

Other: Exercise