Health Effects of Oats and Oat Bioactive in Human

Lund University

Status: Completed

Conditions: Postprandial Glucose Regulation

Treatments: Combination Product: Oat Beverage 4; Combination Product: Control product; Combination Product: Oat Beverage 3; Combination Product: Oat Beverage 1; Combination Product: Oat Beverage 2

Study type: Interventional

Funder types: Other

Identifiers

NCT03830736

Protokoll 2018/8

Details and patient eligibility

About

Aim of the study is to investigate health effects of oats and oat derived components, in human intervention studies, with the purpose to build new knowledge for development of cardiometabolic protective foods.

Full description

The overall goal is to increase the knowledge which can be used for the development of food products with anti-diabetic properties, with the purpose to facilitate healthier food choices for people. More specifically the primary purpose of this project is to evaluate effects in healthy humans on cardiometabolic test markers of oat and oat based product. The new knowledge will form a base for the development of oat based food products with added health values.

Enrollment: 24 patients

Sex: All

Ages: 20 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy adults
• BMI 18,5 - 25
• non smokers
• consuming a non-vegetarian diet that follows the Nordic guidances

Exclusion criteria

• Fasting blood glucose concentration >6.1 mmol/l
• known cardio-metabolic disease (e.g. diabetes, hypertension, metabolic syndrome), gastro-intestinal disorders such as IBS (irritable bowel syndrome) that can interfere with the study results, food allergies. Further no antibiotics or probiotics should have been consumed within 4 weeks prior to and during the study.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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24 participants in 5 patient groups, including a placebo group

Control product

Placebo Comparator group

Description:

A glucose solution (glucose and water) based on 42 gram carbohydrates.

Treatment:

Combination Product: Control product

Oat Beverage 1

Experimental group

Description:

The test product is an oat based beverage with added vegetable oil. The test portion is based on 42 gram available carbohydrates and consumed as a breakfast meal prior to determinations of test variables in the morning.

Treatment:

Combination Product: Oat Beverage 1

Oat Beverage 2

Experimental group

Description:

The test product is an oat based beverage with added vegetable oil. The test portion is based on 42 gram available carbohydrates and consumed as a breakfast meal prior to determinations of test variables in the morning.

Treatment:

Combination Product: Oat Beverage 2

Oat Beverage 3

Experimental group

Description:

The test product is an oat based beverage with added vegetable oil. The test portion is based on 42 gram available carbohydrates and consumed as a breakfast meal prior to determinations of test variables in the morning.

Treatment:

Combination Product: Oat Beverage 3

Oat Beverage 4

Experimental group

Description:

The test product is an oat based beverage. The test portion is based on 42 gram available carbohydrates and consumed as a breakfast meal prior to determinations of test variables in the morning.

Treatment:

Combination Product: Oat Beverage 4