Health Related QOL, Depression and Lifestyle Changes in Insulin Resistant Adolescents

Children's Mercy Hospital Kansas City

Status: Completed

Conditions: Insulin Resistance; Depression

Treatments: Behavioral: Health-Related Quality of Life instrument; Behavioral: Depression Scale for Children (CES-DC)

Study type: Observational

Funder types: Other

Identifiers

NCT00493259

07 02-037E

Details and patient eligibility

About

The purpose of this study is to assess adolescents with Insulin Resistance Syndrome for quality of life and altered health related issues.

Full description

Matched historical control study designed to examine outcomes on insulin resistant adolescents who were treated in the Insulin Resistance Syndrome Clinic at Children's Mercy Hospital in the past year. New patients will be screened at baseline, 4 and 12 months to evaluate if there is improvement in the BMI Z-score, HgA1c, lipid profile or waist circumference when depression and/or altered health related quality of life are identified and treated in this population.

Enrollment: 78 patients

Sex: All

Ages: 11 to 17 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients 11-17 years of age who are seen in the Insulin Resistance Clinic for the first time
• Historical control: Patients 11-19 years of age seen in the Insulin Resistance Clinic during the prior four months

Exclusion criteria

• Co-morbid syndrome (Downs, Turner's, Prader Willi etc)
• Diagnosis of Type 2 Diabetes
• Taking Metformin before the initial visit
• Taking medication for or diagnosis of a psychiatric condition prior to initial visit
• Developmentally delayed