Health-related Quality of Life After Massive Burn Injury (HR - QOL MR)

Civil Hospices of Lyon

Status: Completed

Conditions: Patients With Massive Burn Injury

Treatments: Other: Evaluation of health-related quality of life

Study type: Observational

Funder types: Other

Identifiers

NCT03660150

CRC_GHN_2018_003

Details and patient eligibility

About

Massive burns are serious life-threatening conditions. Recent advances in their management now allow the survival of a growing number of patients. The burn care paradigm is transformed: the evaluation of survival at the end of acute care is no longer sufficient for a good evaluation of practices; the attention now focuses on long-term health-related quality of life (HR-QOL).The recently validated French translation of the burn specific health scale brief version makes this evaluation now feasible in French burn centers. The objectives of this study are to evaluate the HR-QOL of massive burn survivors, to compare it to another chronic condition (necrotizing fasciitis) and to determine the main predictive factor of health-related quality of life. This study is retrospectively conducted in 18 patients who survived a massive burn injury involving more than 80% of the total body surface area, or more than 70% of the total body surface area if the injury occured during childhood and who were treated between 1997 and 2017 in our Lyon burn center. Short Form-36 Medical Outcomes Survey (SF-36), and Brief Version of Burn Specific Health Scale (BSHS-B) are used for the present evaluation.

Full description

The hypotheses are as follows:

• the HR-QOL of massive burns shows a significative alteration compared to general population
• this alteration is comparable with another chronic disease
• the main predictors of impaired quality of life related to physical health status are hand injury, age at time of burn and time since burn
• the main predictive factors of change in quality of life related to mental health status are age of onset and facial involvement.

Enrollment: 18 patients

Sex: All

Ages: 14+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patients over 14 years of age
2. Patients with a childhood burn reaching more than 70% of the total body surface OR Adult patients with burns of more than 80% of total body surface area
3. Patients who were treated at the burn center between January 1997 and January 2017
4. Patients who survived after initial hospitalization for burn management

Exclusion criteria

1. Patients with superficial burning, without sequelae or with extensive sequelae at less than 70% of total body surface area in children and less than 80% of total body surface area in adults
2. Patients who expressed opposition to their participation in the study