Health Status of Patients After Surgically Implanted Biological and Mechanical Aortic Valves: a Population-based Retrospective Analysis (2010-2018)

Medical University of Vienna

Status: Completed

Conditions: Aortic Valve Disease

Treatments: Device: Aortic Valve Replacement

Study type: Observational

Funder types: Other

Identifiers

NCT04900909

AUTHEARTVISIT

Details and patient eligibility

About

The overall project aim is to study outcomes following aortic valve replacement with either mechanical valves or bioprostheses by retrieving data from the main social security carriers in Austria for the years 2010-2018.

Full description

The purpose of this research project is to evaluate mortality (primary outcome) and incidence of heart attack, stroke, reoperation and first diagnosis of heart insufficiency (secondary outcomes) after aortic valve replacement. We aim to compare those outcomes between mechanical valves and bioprostheses.

Data will be retrieved from the main social security carriers in Austria (covering 98% of its population) from 2010-2018.

Enrollment: 13,993 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• isolated surgical aortic valve replacement in Austria

Exclusion criteria

• below 18 years of age
• concomitant heart surgery

Trial design

13,993 participants in 2 patient groups

Aortic valve replacement with mechanical valves

Treatment:

Device: Aortic Valve Replacement

Aortic valve replacement with bioprostheses

Treatment:

Device: Aortic Valve Replacement