Healthy Aging Through Dietary Intervention

Heinrich-Heine University, Duesseldorf

Status: Completed

Conditions: Aging, Healthy

Treatments: Drug: Placebo; Drug: Flavanol

Study type: Interventional

Funder types: Other

Identifiers

NCT05782309

AgingEx

Details and patient eligibility

About

To test the impact of flavanol supplementation of cardiac and vascular function and subsequently on exercise capacity in elderly individuals

Enrollment: 68 patients

Sex: All

Ages: 50 to 79 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age 50-79

Exclusion criteria

• non-cardiac limitations of exercise capacity such as orthopedic or neurological disorders, BMI >35 kg/m2, active smoking, uncontrolled blood pressure, diabetes, COPD, atrial fibrillation, cardiomyopathy, coronary heart disease, valvular heart disease, cardiac pacemaker, acute respiratory tract infections, missing ability or missing cooperation to participate in the study

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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68 participants in 2 patient groups, including a placebo group

Flavanol

Experimental group

Description:

500 mg of flavanols twice daily

Treatment:

Drug: Flavanol

Placebo

Placebo Comparator group

Description:

nutrient matched control capsule

Treatment:

Drug: Placebo