Healthy Nordic Foods to Prevent Cardiometabolic Risk in Obese Subjects

Lund University

Status: Completed

Conditions: Obesity; Diet Modification; Cardiovascular Risk Factor

Treatments: Other: Control diet; Other: Nordic diet

Study type: Interventional

Funder types: Other

Identifiers

NCT03102853

NOVI377

Details and patient eligibility

About

This project will examine whether long-term consumption of healthy Nordic foods can maintain a healthy weight also after weight loss, and decrease abdominal fat accumulation and cardiometabolic risk. The study will be performed with the aim to achieve a substantial body weight loss in the first phase by prescribing a standardized low caloric dietary formula. The follow-up phase will be a body weight-maintenance period and the subjects will be randomised to a healthy Nordic diet group and a control diet group. During the study body weight will be monitored and other measurements will include insulin sensitivity, blood lipids and inflammation markers.

Enrollment: 80 patients

Sex: All

Ages: 25 to 67 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age 25-67 years, BMI 30-40 kg/m2, waist circumference men >102cm and women > 88cm or sagittal abdominal diameter men >22cm and women >20cm, stable body weight

Exclusion criteria

• glucose >7.0 mmol/l, B-Hb1aC >48 mmol/L, triglycerides >4 mmol/l, total cholesterol >8 mmol/l, bloodpressure >160/100 mmHg, chronic disease, gastro-intestinal disease, hyper-/hypothyroidism, alcohol abuse, cancer, gastric bypass operation, gluten allergy, lactose intolerance, pregnancy

Trial design

80 participants in 2 patient groups

Nordic diet

Active Comparator group

Treatment:

Other: Nordic diet

Control diet

Other group

Treatment:

Other: Control diet