Heart Failure-USB: Prediction and Progression

University Hospital Basel

Status: Enrolling

Conditions: Acute Coronary Syndrome; Acute Heart Failure; Heart Failure

Treatments: Other: data generated by direct IT export; Other: medical chart review

Study type: Observational

Funder types: Other

Identifiers

NCT04000061

2019-00956 me19Mueller;

Details and patient eligibility

About

This retrospective cohort study is to identify triggers of heart failure (HF) development and drivers of HF progression as well as the underlying cardiac disease (phenotype) to identify patients at risk and predict the clinical course of the disease. Data of patients who were hospitalized during the years 2010-2023 with acute coronary syndrome (ACS) and/ or with acute heart failure (AHF) will be collected and analyzed. In a subgroup cohort efficacy and safety of digoxin in patients with acute heart failure triggered by tachyarrhythmia will be evaluated.

Enrollment: 6,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients hospitalized with a primary diagnosis of ACS
• Patients hospitalized with a primary or secondary diagnosis of AHF

Exclusion criteria

• Existence of a documented statement of the patient against the scientific use of clinical data

Trial design

6,000 participants in 2 patient groups

acute coronary syndrome (ACS)

Description:

Outcome information (all-cause death, heart failure (HF) hospitalizations) of patients hospitalized with a primary diagnosis of ACS is analyzed.

Treatment:

Other: medical chart review

Other: data generated by direct IT export

acute heart failure (AHF)

Description:

Outcome information (all-cause death, heart failure (HF) hospitalizations) of patients hospitalized with a primary or secondary diagnosis of AHF is analyzed.

Treatment:

Other: medical chart review

Other: data generated by direct IT export