Heart Failure With Mildly Reduced Ejection Fraction Registry (HARMER)

Universitätsmedizin Mannheim

Status: Enrolling

Conditions: Heart Failure

Study type: Observational

Funder types: Other

Identifiers

NCT05603390

2022-818

Details and patient eligibility

About

Heart failure (HF) affects about 1% of patients younger than 55 years, whereas the prevalence of HF increases > 10% in patients with at least 70 years of age. Despite HF with reduced ejection fraction (HFrEF) and HF with preserved ejection fraction (HFpEF), the clinical significance of HF with mildly reduced ejection fraction (HFmrEF) has gained more importance within the past years. Those patients are characterized by a left ventricular ejection fraction (LVEF) of 41-49%. However, within the current European guidelines, limited treatment recommendations in this subgroup of HF are yet available as a consequence of the limited number of studies in this field. The "Heart Failure With Mildly Reduced Ejection Fraction Registry" aims to characterize patients with HFmrEF and investigated the prognostic impact of interventional and pharmacological therapies in this subgroup of HF patients.

Enrollment: 2,200 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with HFmrEF (i.e., LVEF 41-49%)
• Patients with at least 18 years of age

Exclusion criteria

• Patients younger than 18 years of age