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Heart Rate and Initial Presentation of Cardiovascular Diseases (Caliber)

University College London (UCL) logo

University College London (UCL)

Status

Unknown

Conditions

Coronary Heart Disease NOS
Ischemic Stroke
Unstable Angina
Stroke
Transient Ischemic Attack
Myocardial Infarction
Heart Failure
Subarachnoid Haemorrhage
Peripheral Arterial Disease
Cardiac Arrest, Sudden Cardiac Death
Intracerebral Haemorrhage
Unheralded Coronary Death
Stable Angina Pectoris
Abdominal Aortic Aneurysm

Study type

Observational

Funder types

Other

Identifiers

NCT01947361
12_153R_IP10
RP-PG-0407-10314 (Other Grant/Funding Number)

Details and patient eligibility

About

Study of heterogeneity in associations between heart rate and the initial presentation of 12 cardiovascular diseases.

Full description

This study is part of the CALIBER (Cardiovascular disease research using linked bespoke studies and electronic records) programme funded over 5 years from the NIHR and Wellcome Trust. The central theme of the CALIBER research is linkage of the Myocardial Ischaemia National Audit Project (MINAP) with primary care (GPRD) and other resources. The overarching aim of CALIBER is to better understand the aetiology and prognosis of specific coronary phenotypes across a range of causal domains, particularly where electronic records provide a contribution beyond traditional studies. CALIBER has received both Ethics approval (ref 09/H0810/16) and ECC approval (ref ECC 2-06(b)/2009 CALIBER dataset).

Enrollment

1,961,286 patients

Sex

All

Ages

30+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • One year prior to study entry (up-to-standard follow-up, CPRD quality research standard).
  • > 30 years old
  • have at least a recorded heart rate measurement during the study period

Exclusion criteria

  • Evidence of prior atherosclerotic or cardiac disease

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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