Heart Rate Variability and Nocturnal Blood Oxygen Saturation in Patients With Idiopathic Pulmonary Fibrosis

Taipei Veterans General Hospital

Status: Enrolling

Conditions: Idiopathic Pulmonary Fibrosis

Treatments: Device: "LARGAN" ECG Holter

Study type: Observational

Funder types: Other

Identifiers

NCT06027372

2020-04-016BC

Details and patient eligibility

About

The goal of this observational study is to compare the overnight heart rate variability (HRV) and nocturnal oxygen saturation (SpO2) in patients with idiopathic pulmonary fibrosis (IPF). The main questions it aims to answer are: (1). if there are correlations between pulmonary function test and HRV and overnight SpO2; (2). if HRV and SpO2 can predict the occurrence of acute exacerbation in patients with IPF. Participants will be asked to examine pulmonary function test (including lung volumes and six-minute walk test) and wear pulse oxygenation recorder and "LARGAN" ECG Holter" ("LARGAN HEALTH TECHNOLOGY" Sleep Apnea And Sleep Quality Examination System) during sleep.

Enrollment: 70 estimated patients

Sex: All

Ages: 50+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• individuals meet the diagnosis of idiopathic pulmonary fibrosis
• individuals agree to participate this study and sign the informed consent
• individuals have cognitive and behavioral abilities

Exclusion criteria

• age less than 50 years old
• individuals refuse to participate this study and sign the informed consent
• individuals of unclear consciousness

Trial design

70 participants in 2 patient groups

IPF patients with acute exacerbation during test period

Description:

IPF patients completing pulmonary function, overnight SpO2 monitor and "LARGAN" ECG Holter reqire hospitalization during test period.

Treatment:

Device: "LARGAN" ECG Holter

IPF patients without acute exacerbation during test period

Description:

IPF patients completing pulmonary function, overnight SpO2 monitor and "LARGAN" ECG Holter remain stable during test period.

Treatment:

Device: "LARGAN" ECG Holter