Heliox in Preterm Infants With Respiratory Distress Syndrome

Third Military Medical University

Status: Completed

Conditions: Respiratory Distress Syndrome

Treatments: Other: heliox

Study type: Interventional

Funder types: Other

Identifiers

NCT01759316

Lixue

Details and patient eligibility

About

Heliox can lower respiratory resistance, improve the oxygenation, reduce respiratory distress and lung injury caused by mechanical ventilation.

Full description

Heliox can improve the oxygenation, reduce respiratory distress and lung injury caused by mechanical ventilation.

Heliox has not been widely used. More studies on the effects and safety of Heliox in addition to NIPPV and mechanical ventilation should be tried.

Enrollment: 36 patients

Sex: All

Ages: 28 to 37 weeks old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Gestational age more than 28 weeks and less than 32 weeks
• Diagnosed as respiratory distress syndrome
• Need to use NIPPV ventilation
• No congenital diseases or hereditary diseases
• With an informed consent form

Exclusion criteria

• With congenital diseases or hereditary diseases
• Intubated in the delivery room
• Need surgery

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: Single Blind

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36 participants in 2 patient groups, including a placebo group

heliox

Active Comparator group

Description:

Heliox is use in this group

Treatment:

Other: heliox

Placebo

Placebo Comparator group

Description:

Oxygen is used in this group

Treatment:

Other: heliox