Hematology Biobank: In Vitro Study of Blood Disorders

Albert Einstein College of Medicine

Status: Enrolling

Conditions: Hematological Disorders

Study type: Observational

Funder types: Other

Identifiers

NCT02442011

2013-2918

Details and patient eligibility

About

This is a biorepository of blood specimens from subjects with different Hematological disorders.

Full description

There has been a marked increase in our knowledge of Blood Disorders in the last decade. Much of this knowledge comes from examining blood specimens from patients and subjecting these samples to red cell, plasma, serum or DNA analyses. The study team proposes to set up a Hematology biobank, which will include patient histories, their medical progress and a linked but de-identified bank of blood samples. This will enable researchers to have a large database, which can be used to learn more about these diseases.

The Hematology biobank will use whole blood, red blood cells, plasma, serum and/or DNA. Whole blood specimens, which by definition include the white cells that contain DNA, will be collected and stored in the biobank repository at the Institute for Clinical and Translational Research (ICTR) for future studies.

Blood samples will be obtained from two sources:

1. Leftover/discarded whole blood samples that were obtained for standard of care.
2. Blood samples consisting of 1-5 tubes (3-20 ml of whole blood) from patients with written consent. When possible, these samples will be obtained during routine blood draws performed for a typical visit. It may be necessary to ask patients to specifically donate blood for the study.

Enrollment: 2,000 estimated patients

Sex: All

Ages: 12+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Above 12 years of age and referred to the Hematology Division at Montefiore-Einstein
• Under the care of a Montefiore-Einstein hematologist for a hematologic disorder

Exclusion criteria

- Do not meet the Inclusion Criteria listed above