Hemi-Gland Cryoablation for Prostate Cancer at UCLA

Jonsson Comprehensive Cancer Center

Status: Invitation-only

Conditions: Prostate Disease; Prostate Adenocarcinoma; Prostate Cancer

Treatments: Device: Hemigland Cryoablation

Study type: Observational

Funder types: Other

Identifiers

NCT03503643

17-001084

Details and patient eligibility

About

This is a prospective data collection of men who are electing to undergo prostate hemi-gland cryoablation.

The purpose of this observational research study is to investigate the localized treatment of prostate cancer using hemi-gland cryoablation.

UCLA patients undergoing hemi-gland cryoablation are a unique cohort compared to prior research because all patients at UCLA have had a pre-treatment multi-parametric MRI and Ultrasound fusion targeted biopsy; they will be followed in a similar fashion. This results in more precise assessment of a target region of cancer for ablation which may, in turn, result in improved clinical outcomes.

Enrollment: 100 estimated patients

Sex: Male

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient has undergone or has elected to undergo hemi-gland cryoablation at UCLA
• Low or intermediate risk prostate cancer (Gleason ≤ 7) or select high-risk patients (Gleason 8 prostate cancer).
• Prostate volume of ≤ 70 cc
• Ability to complete informed consent form

Exclusion criteria

• Medical contraindication to follow-up multi-parametric magnetic resonance imaging (mpMRI) or prostate biopsy
• Patients unable to tolerate general or regional anesthesia.