Hemodilution and Outcome in Cardiac Surgery

Università Vita-Salute San Raffaele

Status: Terminated

Conditions: Kidney Failure; Intraoperative Complications

Treatments: Procedure: Different timing of red blood cells transfusion (substudy 1); Acute hemodilution versus no hemodilution (substudy 2)

Study type: Interventional

Funder types: Other

Identifiers

NCT00364494

DS/URC/ER/mm 556/DG

Details and patient eligibility

About

An hematocrit of 21-25% is supposed to perform the best organ protection during cardiopulmonary bypass for cardiac surgery.

The investigators want to establish the best timing for a transfusion (in patients with a predicted low hematocrit during cardiopulmonary bypass) and the efficacy of preprocedural hemodilution (in patients with a predicted high hematocrit during cardiopulmonary bypass) in patients undergoing cardiac surgery.

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Undergoing cardiac surgery

Exclusion criteria

• Age < 18 years old
• Not signing written consent
• Age < 65 years old (subgroup 1)
• Emergency, aortic stenosis, main left coronary stenosis (subgroup 2)

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind