Hemodynamic Comparison of Peripheral and Central VA ECMO. (RECOVERY)

Xi'an Jiaotong University

Status: Enrolling

Conditions: Hemodynamics Instability; Extracorporeal Circulation; Complications; Cardiac Arrest; Shock, Cardiogenic

Treatments: Procedure: Veno-arterial extracorporeal membrane oxygenation

Study type: Observational

Funder types: Other

Identifiers

NCT05669183

XJTU1AF2021CRF-005

Details and patient eligibility

About

The goal of this clinical trial is to monitor hemodynamic differences between central veno-arterial extracorporeal membrane oxygenation (VA ECMO) and peripheral VA ECMO. The main question it aims to answer is:

• Efficacy of the different cannulation strategies for the establishment of for VA-ECMO circulation on hemodynamics and organ perfusion.

Participants require VA ECMO support, will be divided into two groups in an intention-to-treat analysis: central artery cannulation and peripheral artery cannulation.

Researchers will analyze different cannulation strategies for VA-ECMO and identify potential advantages and disadvantages for two groups of VA-ECMO.

Enrollment: 136 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age≥18 years
• Participants with cardiogenic shock
• Obtaining informed consent from participants or their affiliated beneficiaries

Exclusion criteria

• Irreversible heart failure
• Contraindications to anticoagulation therapy
• Uncontrolled bleeding
• Irreversible neurological pathology
• Participants limited to extracorporeal cardiopulmonary resuscitation

Trial design

136 participants in 2 patient groups

Peripheral VA ECMO

Description:

Femoral artery cannulation for veno-arterial extracorporeal membraneous oxygenation (VA ECMO)

Treatment:

Procedure: Veno-arterial extracorporeal membrane oxygenation

Central VA ECMO

Description:

Axillary artery cannulation for veno-arterial extracorporeal membraneous oxygenation (VA ECMO)

Treatment:

Procedure: Veno-arterial extracorporeal membrane oxygenation