Hemodynamic Effects of Negative Pressure Ventilation in Chronic Obstructive Pulmonary Disease

Fu Jen Catholic University

Status: Completed

Conditions: COPD

Treatments: Other: Received negative pressure ventilation

Study type: Observational

Funder types: Other

Identifiers

NCT04212559

C107137

Details and patient eligibility

About

Negative pressure ventilation (NPV) is a non-invasive ventilation mode which provide better lung expansion. The major complication of NPV is decrease blood pressure and affects the hemodynamics. The effects of NPV on chronic obstructive pulmonary disease (COPD) patients with pulmonary rehabilitation program remains unknown.

Full description

Both of NPV or positive pressure ventilation (PPV) has impact of hemodynamics. NPV with cuirass ventilator increases venous return and leads to ventricular filling and increases cardiac output (CO); In contrast to NPV, the effect of PPV in most situations is a decreased venous return and leads to decreased CO. NPV improving ventilation and work of breathing in patients with chronic obstructive pulmonary disease (COPD).

Enrollment: 30 patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with COPD who received pulmonary rehabilitation program with NPV treatment

Exclusion criteria

• Recent exacerbation within 3-months
• Existing of tracheostomy
• Absence of NPV used
• Required of oxygen supplement during NPV
• Diagnosed of neuromuscular disease

Trial design

30 participants in 1 patient group

NPV group

Description:

Patients who had treated in pulmonary rehabilitation unit with NPV

Treatment:

Other: Received negative pressure ventilation