Hemodynamic Effects of Ventilation Modes

Ufuk University

Status: Unknown

Conditions: Laparoscopy; Respiration, Artificial; Hemodynamics

Treatments: Procedure: Mode of Mechanical Ventilation

Study type: Observational

Funder types: Other

Identifiers

NCT03684291

HemodynamicsTrendelenburg

Details and patient eligibility

About

Different ventilation modes can be used in laparoscopic surgeries. These surgeries are performed in steep Trendelenburg position with serious hemodynamic disturbances. This study aims to observe the hemodynamic effects of two different ventilation modes in laparoscopic gynecologic surgery performed in steep Trendelenburg position.

Enrollment: 30 estimated patients

Sex: Female

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Women of ASA I and II classification between 18-65 years scheduled for elective gynecologic laparoscopic surgery

Exclusion criteria

• Patient refusal to participate
• Patients with severe cardiac (congestive heart failure etc) and pulmonary (COPD, pulmonary hypertension) disease (ASA > III)
• Morbid obesity
• Negative Allen test

Trial design

30 participants in 2 patient groups

Group V

Description:

The patients in this group are ventilated using VCV (Volume Control Ventilation) mode (FiO2 50%, Tidal volume: 6-8 ml/kg (ideal body weight), frequency: 12/minute, I/E ratio: 1/2, PEEP not applied)

Treatment:

Procedure: Mode of Mechanical Ventilation

Group P

Description:

The patients in this group are ventilated using PCV-VG (Volume Guaranteed Pressure Control Ventilation) mode (FiO2 50%, Tidal volume: 6-8 ml/kg (ideal body weight), frequency: 12/minute (EtCO2 kept between 35-40 mmHg), Pressure limit: 30 cm H2O, I/E:1/2, PEEP not applied)

Treatment:

Procedure: Mode of Mechanical Ventilation