Hemodynamic Optimization Based on a Dynamic Elastance Protocol

Institute of Hospitalization and Scientific Care (IRCCS)

Status: Completed

Conditions: Fluid Management

Treatments: Behavioral: Elastance Group

Study type: Interventional

Funder types: Other

Identifiers

NCT05187273

ID3724

Details and patient eligibility

About

In this study investigators explore the effects of a dynamic elastance guided protocol compared to a stroke volume variation fluid therapy on lactate levels during major abdominal surgery. Hence investigators created two groups: in the intervention group fluids are given in fluid-responders (SVV > 13%) based on high value of dynamic elastance (ie. Eadyn > 0.9). In the standard group fluids are administered when SVV > 13%.

Enrollment: 46 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: patients enrolled for major abdominal surgery

Exclusion Criteria:

1. end-stage renal disease
2. severe heart dysfunction
3. heart rhythm alterations

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Sequential Assignment

Masking: Single Blind

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46 participants in 2 patient groups

intervention

Experimental group

Treatment:

Behavioral: Elastance Group

control

No Intervention group