Hemodynamics Monitoring During Lower Body Negative Pressure (LBNP) Induced Controlled Hypovolemia (LBPN)

Yale University

Status: Enrolling

Conditions: Hypovolemia; Hemodynamic Instability

Treatments: Diagnostic Test: Lower body negative pressure

Study type: Observational

Funder types: Other

Identifiers

NCT03592290

000

2000020057

Details and patient eligibility

About

To monitor the changes in central and peripheral monitors/waveforms during gradual hypovolemia induced by lower body negative pressure in healthy volunteers.

Full description

The primary aim of this research is to identify the most robust site for monitoring hypovolemia as well as assess changes in peripheral waveforms monitored by the pulse oximeter collected from different sites (finger, ear, forehead, and nose), blood pressure, cerebral oximetry and peripheral venous pressure during gradual hypovolemia induced by lower body negative pressure (LBNP) in healthy volunteers.

Enrollment: 120 estimated patients

Sex: All

Ages: 20 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

* Healthy volunteers aged 20-45 with

Exclusion criteria

• Pregnant women
• Under 20 years of age
• Subjects with coronary artery disease, diabetes, epilepsy and hypertension