Hemostasis Achievement Reflecting Inflammatory Status of the Pulp Based on Cytokine Levels: A Cohort Study.

Cairo University (CU)

Status: Completed

Conditions: Hemorrhage

Treatments: Diagnostic Test: ENzyme linked immunity-sorbet assays

Study type: Observational

Funder types: Other

Identifiers

NCT03737682

CEBD-CU-2018-10-31

Details and patient eligibility

About

Assessment of pulp inflammation by hemostasis achievement after pulp exposure

Full description

The possibility has been raised of diagnosing pulpal pathological status using the cytokines that are released during the inflammation process in healthy as well as infected tooth pulp. Cytokines are small polypeptides secreted by leucocytes and other inflammatory cells and are known to play important roles in the intensity and duration of the immune response

Enrollment: 41 patients

Sex: All

Ages: 5 to 7 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. healthy children

2. patients had not used any inflammatory medications

3. primary molar teeth of these children were included based on the following clinical and radiographic criteria:

   1. no clinical symptoms or evidence of pulp degeneration (pain on percussion, history of swelling or sinus tract
   2. no spontaneous pain
   3. no radiographic signs of internal or external resorption, widened periodontal ligament space, or furcal/periapical radiolucency
   4. physiological root resorption of no more than one third the root length
   5. a deep caries lesion with a likelihood of pulp exposure during caries removal

Exclusion criteria

• patients used any anti-inflammatory medication

Trial design

41 participants in 2 patient groups

hemostasis achievement

Description:

in which hemostasis at the exposure site was achieved in five minutes were included in group A

Treatment:

Diagnostic Test: ENzyme linked immunity-sorbet assays

No hemostasis achievement

Description:

in which hemostasis at the exposure site couldn't be achieved in five minutes where included in group B

Treatment:

Diagnostic Test: ENzyme linked immunity-sorbet assays