Hemostatic Profile of Post COVID-19/Long COVID-19 Patients (LCV)

San Donato Group (GSD)

Status: Completed

Conditions: COVID-19; Post-acute COVID-19 Syndrome

Treatments: Other: Interview; Diagnostic Test: Laboratory analysis; Diagnostic Test: ClotPro assessment

Study type: Observational

Funder types: Other

Identifiers

NCT05721066

LONG-COVID-VET

Details and patient eligibility

About

The present study aims at assessing long-term hemostatic profile of patients recovered from COVID-19 acute infection that remain asymptomatic (POST-COVID) versus patients with residual symptoms (LONG-COVID) through the employment of a commercially available new generation point-of-care viscoelastic device. The primary endpoint is based upon the hypothesis that patients with residual symptoms maintain an abnormal coagulation profile even after recovery from COVID-19.

Enrollment: 102 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age > 18 years;
• recovery from acute COVID-19 infection;
• COVID-19 pneumonia that required hospitalization in our Institution;
• discharge from the hospital minimum 3 months before the day of the visit;
• written consent to participate to the study.

Exclusion criteria

• none.

Trial design

102 participants in 2 patient groups

POST-COVID

Description:

Patients hospitalized due to acute COVID-19 pneumonia and discharged home. No residual symptoms after recovery. Contacted by phone and invited to an in-person interview about their health conditions and a blood withdrawal for the assessment of the coagulation profile (both in standard laboratory and point-of-care device ClotPro).

Treatment:

Other: Interview

Diagnostic Test: ClotPro assessment

Diagnostic Test: Laboratory analysis

LONG-COVID

Description:

Patients hospitalized due to acute COVID-19 pneumonia and discharged home. Presence of residual symptoms after recovery or new symptoms appeared after discharge not otherwise explained. Contacted by phone and invited to an in-person interview about their health conditions and a blood withdrawal for the assessment of the coagulation profile (both in standard laboratory and point-of-care device ClotPro).

Treatment:

Other: Interview

Diagnostic Test: ClotPro assessment

Diagnostic Test: Laboratory analysis