Heparin-induced Thrombocytopenia (HIT II) in Liver Transplant Recipients (HITOLT)

CHIR-Net

Status: Completed

Conditions: Liver Transplantation; Heparin-induced Thrombocytopenia

Study type: Observational

Funder types: Other; NETWORK

Identifiers

NCT01654848

HITafterOLT (Other Identifier)

TransplanTUM-1

Details and patient eligibility

About

In a prospective observational study the incidence of Heparin-induced Thrombocytopenia (HIT) Type 2 after orthotopic liver transplantation, associated factors, and hemostaseological findings in thrombocytes and anti-body patterns is going to be investigated.

Full description

The investigators examined the frequency of anti-PF4/heparin antibodies (IgG/M/A; EIA) and their functional activity (HIPA) in 38 whole organ deceased donor liver transplant recipients. Additionally, demographic, clinical, donor- and recipient-specific parameters and laboratory findings (ALAT, ASAT, cholinesterase) were investigated.

Enrollment: 39 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• all consecutive liver transplant recipients between 01/2010 and 08/2011 who
• were transplanted at our center after allocation of a liver graft via Eurotransplant

Exclusion criteria

• patient's refusal to participate in prospective observation

Trial design

39 participants in 1 patient group

orthotopic Liver Transplantation

Description:

consecutive inclusion of all recipients