Heparin Resistance: Predictors and Outcomes

Yonsei University

Status: Completed

Conditions: Off Pump Coronary Artery Bypass Surgery

Treatments: Drug: Heparin

Study type: Interventional

Funder types: Other

Identifiers

NCT01044888

4-2007-0142

Details and patient eligibility

About

The investigators evaluated clinical impact of reduced heparin responsiveness (HRreduced) on the incidence of perioperative myocardial infarction (MI) and restenosis at 6 months after off-pump coronary artery bypass graft surgery (OPCAB) and identified its predictors.

Enrollment: 199 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• enrolling all consecutive patients scheduled for elective isolated multivessel OPCAB between April 2007 and March 2008

Exclusion criteria

• presence of known preoperative coagulopathy, emergency operation or preoperative use of an intra-aortic balloon pump.

Trial design

Primary purpose: Supportive Care

Allocation: N/A

Interventional model: Single Group Assignment

Masking: Single Blind