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Heparin Versus Saline in Peripheral Venous Catheter

H

Hospital General Universitario Gregorio Marañon

Status

Completed

Conditions

Catheter-Related Infections

Treatments

Device: Heparin
Device: saline

Study type

Interventional

Funder types

Other

Identifiers

NCT02970409
FIBHGM-ECNC002-2014

Details and patient eligibility

About

A clinical, prospective. controlled and randomized study with patients with a peripheral venous catheter. Patients will be randomized to either receive heparin or saline. The investigators will monitored the clinical out come to further evaluate catheter colonization rate, phlebitis rate, days of hospital stay, antimicrobial costs, and adverse effects.

Full description

The need of use of peripheral venous catheters and the importance of a proper management to avoid catheter colonization or phlebitis requires two possible preventive approaches: lock therapy with heparin or saline.

Heparin demonstrated its efficacy in central venous catheters, but there are still controversies of whether it is useful in peripheral venous catheters.

Objectives To compare the efficacy of heparin in peripheral venous catheters lock versus saline for the prevention of colonization and phlebitis in patients admitted to an Internal Medicine Department.

Methods: A clinical, prospective. controlled and randomized study with patients with a peripheral venous catheter.

Patients will be randomized to either receive heparin or saline. The investigators will monitored the clinical out come to further evaluate catheter colonization rate, phlebitis rate, days of hospital stay, antimicrobial costs, and adverse effects.

Enrollment

354 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • patients with inserted PV Catheter within 24h from admission in internal medicine

Exclusion criteria

  • hypersensibility to heparin
  • active hemorrhage
  • coagulation alterations

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

354 participants in 2 patient groups

heparin
Active Comparator group
Description:
Catheter Lock Therapy with Heparin
Treatment:
Device: Heparin
saline
Experimental group
Description:
Catheter Lock Therapy with saline
Treatment:
Device: saline

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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