Hepatic Artery Stenosis and Thrombosis After Liver Transplantation in Children (HEPATIC)

University Medical Center Groningen (UMCG)

Status: Invitation-only

Conditions: Liver Transplant; Complications; Hepatic Artery Stenosis; Pediatric ALL; Hepatic Artery Thrombosis

Study type: Observational

Funder types: Other

Identifiers

NCT05818644

17033

Details and patient eligibility

About

The goal of this observational study is to investigate the incidence, current management practices, and outcomes in pediatric patients with HAC after liver transplantation.

Research question:

• What are the overall incidence of HAC and the effectiveness of all treatment strategies for HAC after pediatric LT?
• What are the current management practices in the experience of centers, anticoagulant therapy, screening protocol, and assessment criteria for HAC after pediatric LT?

The burden of participation is considered to be minimal, and limited to the questionnaires.

Enrollment: 400 estimated patients

Sex: All

Ages: Under 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Liver transplantation between January 1st 2002 and January 1st 2022, diagnoses of HAC after LT
• The age of the patient is below 18 years at the time of diagnosis and intervention
• The date of diagnosis of HAC or intervention was before January 1st 2023. HAC occurring after first or subsequent LTs are included.

Exclusion criteria

N/A

Trial design

400 participants in 4 patient groups

Conservative treatment

Surgical revascularization

Endovascular revascularization

Re-transplantation