Hepatitis B Virus Infection After Liver Transplantation in Children

Qiu Li

Status: Enrolling

Conditions: Hepatitis B Infection

Study type: Observational

Funder types: Other

Identifiers

NCT03865966

2019-24

Details and patient eligibility

About

China is a highly prevalent area of hepatitis B virus（HBV） infection, with at least 75 million hepatitis B virus carriers, and 80% of primary hepatocellular carcinoma (HCC) is associated with chronic hepatitis B virus infection. Liver transplantation is currently the preferred method for end-stage liver disease such as biliary atresia and cirrhosis in children. In recent years, children's liver transplantation has developed rapidly and the number of developments has increased significantly. If there is chronic hepatitis B virus infection in the donor liver, it may cause HBV transmission, or the patient may have a low-load occult hepatitis B virus infection, and after immunosuppressive treatment, it may lead to hepatitis B virus infection after surgery.

Enrollment: 100 estimated patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with end-stage liver disease who require liver transplantation

Exclusion criteria

• Children without liver transplantation refer to children;
• Children who are unwilling to participate;