Hepatitis B Virus Reactivation in COVID-19 (HBV-C19)

University Medical Centre Ljubljana

Status: Completed

Conditions: COVID-19 Pneumonia; Hepatitis B; Hypoxemia

Treatments: Diagnostic Test: Hepatitis B virus infection

Study type: Observational

Funder types: Other

Identifiers

NCT07154212

HBV in covid

Details and patient eligibility

About

The aim of this observational cohort study was to evaluate adherence to hepatitis B virus (HBV) screening guidelines in a country characterized by low HBV prevalence and assess the potential reactivation and progression of HBV infection in anti-HBV core antigen antibodies (anti-HBc) positive patients receiving corticosteroids for coronavirus disease 2019 (COVID-19).

Enrollment: 1,793 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• hospitalized adult patients with a positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ribonucleic acid (RNA) polymerase chain reaction (PCR) test
• supplemental oxygen
• treated with corticosteroids for COVID-19 pneumonia

Exclusion criteria

• age under 18 years
• hospitalized for medical conditions unrelated to COVID-19
• received corticosteroid therapy for non-COVID-19 reasons

Trial design

1,793 participants in 1 patient group

Hepatitis B virus infected patients receiving corticosteroids for COVID-19 pneumonia

Treatment:

Diagnostic Test: Hepatitis B virus infection