Hepatitis C Diagnosis to Treatment Management

Epividian

Status: Completed

Conditions: Hepatitis C

Treatments: Other: Hepatitis C Treatment Alerts in CHORUS™; Other: Standard of Care

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT05725109

COL2023-001

Details and patient eligibility

About

The objective of this study is to evaluate whether sending alerts to healthcare providers and clinic staff to identify patients with untreated hepatitis C infection can increase the uptake of hepatitis C treatment. A period of time without alerts will be compared to a period of time with alerts.

Full description

The hepatitis C virus (HCV) is one of the most common bloodborne pathogens in the United States. A large proportion of people with HCV infection progress to chronic HCV infection despite the availability of effective treatment; chronic infection can result in cirrhosis, end-stage liver disease, liver cancer, and liver-related death. HCV infection can be cured most of the time with treatment. The objective of this before and after study is to evaluate whether sending alerts to healthcare providers and clinic staff to identify patients with untreated hepatitis C infection can increase the uptake of HCV treatment. A period of time without alerts will be compared to a period of time with alerts. Healthcare providers and clinic staff will not receive alerts during the before period of the study. Healthcare providers and clinic staff will receive alerts during the after period of the study.

Enrollment: 1,063 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18+ years of age
• In care at an AIDS Healthcare Foundation Healthcare Center
• Active, untreated HCV infection

Exclusion criteria

• <18 years of age
• Patients with active HCV infection who have a current prescription for HCV treatment

Trial design

1,063 participants in 2 patient groups

Before Period (1/16/2022 to 10/17/2022)

Description:

All AIDS Healthcare Foundation Healthcare Centers will be contributing to the before phase of this study. In the before phase, alerts identifying patients with active hepatitis C infection will NOT be disseminated to healthcare providers and clinic staff. Routine clinical care will be administered without knowledge of the intervention.

Treatment:

Other: Standard of Care

After Period (1/16/2023 to 10/17/2023)

Description:

All AIDS Healthcare Foundation Healthcare Centers will be contributing to the after phase of this study. In the after phase, alerts identifying patients with active hepatitis C infection will be disseminated to healthcare providers and clinic staff.

Treatment:

Other: Hepatitis C Treatment Alerts in CHORUS™