Hepato-duodenal Ligament Occlusion and Classic Technique in Liver Transplant

Assiut University

Status: Unknown

Conditions: Liver Transplant

Treatments: Procedure: Surgical technique surgical occlusion

Study type: Observational

Funder types: Other

Identifiers

NCT04265157

LDLT

Details and patient eligibility

About

Liver transplantation was historically associated with massive blood loss. Many factors have contributed to the decline in bleeding and transfusion in the past two decades including refinement of surgical techniques, anesthetics management and the use of point of care guided goal-directed hemostatic therapies. Increasing awareness of the adverse associations of allogenic transfusion has driven the quest for transfusion-free transplantation. Pre-operative management of preoperative anemia and targeted correction of coagulopathy is done to decrease blood transfusion. Liver transplantation is associated with the potential for massive operative blood loss, which has been recognized as one of the main causes of morbidity and mortality after liver transplantation. Therefore, a fine surgical procedure to reduce intraoperative hemorrhage is necessary for favorable outcomes of liver transplantation.

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients undergoing Living Donor Liver Transplantation accepted according to hospital protocol
• All patients with liver Cirrhosis who have Porto systemic collaterals based on ct angiography

Exclusion criteria

• Acute fulminant liver failure

Trial design

50 participants in 2 patient groups

Early occlusion of hepatoduodenal ligament

Description:

Early occlusion of hepatoduodenal ligament during mobilization of the liver of the recipient by using portal vein clamp or occlusive temporary bands.

Treatment:

Procedure: Surgical technique surgical occlusion

classical occlusion of hepatoduodenal ligament

Description:

classical occlusion of hepatoduodenal ligament after mobilization of the liver of the recipient immediately before explantation by suing of portal vein clamp

Treatment:

Procedure: Surgical technique surgical occlusion