Hepatocellular Carcinoma Registry in Asia: The INSIGHT Registry

National Cancer Centre, Singapore

Status: Completed

Conditions: Hepatocellular Carcinoma

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT03233360

AHCC08 INSIGHT

Details and patient eligibility

About

The INSIGHT ('Insight into Real-world Practice of Management of HCC in Asia-Pacific') registry is designed as a multi-centre longitudinal cohort study of patients diagnosed with HCC between 1st January 2013 and 31st December 2019 in nine countries (i.e., South Korea, Taiwan, Thailand, Japan, China, Hong Kong, Australia, New Zealand and Singapore). Approximately 30% of the sample size will be identified retrospectively and 70% will be identified prospectively from the start date of the registry (October 2016), with an even distribution of consecutively diagnosed patients within the different years.

Enrollment: 2,533 patients

Sex: All

Ages: 21 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Female or male aged 21 or above.

• Patient with confirmed diagnosis of HCC between 1st January 2013 and 31st December 2019 based on one or more of the following criteria:

  • American Association for the Study of Liver Diseases (AASLD) criteria
  • Asian Pacific Association for the Study of the Liver (APASL) criteria
  • Histology/cytology
  • Space occupying lesion in the liver and an serum alpha-feto protein of > 400 ng/mL in a patient with chronic viral hepatitis or cirrhosis from any cause

• Informed consent form (ICF) to be presented and signed by patients who are still alive at the point of study enrolment, per local regulations. For the collection of data for deceased subjects, appropriate waiver of consent as per local regulations and guidelines will have to be in place.

• Patient who is being followed-up at the participating site.

Exclusion criteria

• Patients participating in any HCC-related therapeutic/interventional clinical trial.