Hepcidin Levels in Preterm Infants

Clalit Health Services

Status: Completed

Conditions: Anemia of Prematurity; Preterm Infants; Neonatal Sepsis

Study type: Observational

Funder types: Other

Identifiers

NCT01539356

0154-11-MMC

Details and patient eligibility

About

A recently isolated peptide hormone, hepcidin, is thought to be the principal regulator of iron homeostasis. Hepcidin acts by limiting intestinal iron absorption and promoting iron retention in reticuloendothelial cells. The aims of this study were to determine serum hepcidin levels in preterm infants who receive blood transfusion and preterm infants having sepsis, in order to assess possible relationships between hepcidin and serum iron, serum ferritin,in iron load situations.

Enrollment: 62 patients

Sex: All

Ages: 24 to 37 weeks old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Preterm < 38 weeks gestation
• Need of blood test for anemia or suspected sepsis

Exclusion criteria

• Major congenital anomalies
• Birth Asphyxia

Trial design

62 participants in 1 patient group

preterm infants

Description:

preterm infants receiving blood transfusion preterm infants with neonatal sepsis.