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Heredity of Retinal Vessel Tortuosity

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Glostrup University Hospital, Copenhagen

Status

Completed

Conditions

Retinopathy of Prematurity

Study type

Observational

Funder types

Other

Identifiers

NCT00427063
Danish Twin Registry 1998

Details and patient eligibility

About

The purpose of this study is to asses the relative influence of genetic and environmental influence on the tortuosity of retinal arterioles in eyes of 218 healthy Danish twins aged 20-46 years. We expect to find a high heredity for the variation in tortuosity. This knowledge can contribute to the elucidation of the pathology in retinal diseases.

Full description

All persons underwent an ophthalmic examination including refraction, slit lamp biomicroscopy and digital fundus photography. Two independent graders (both with an MD degree) made a visual grading of the severity of tortuosity of the retinal arterioles in the fundus images.

Sex

All

Ages

20 to 46 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Samesex twin pairs of self-assessed good health

Exclusion criteria

  • Diabetes mellitus
  • Hypertension
  • Thyroid disease
  • Cataract or other opacities of the refractive media
  • Missing fundus photographs

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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