HES and Acute Kidney Injury in Adult Cardiac Surgery

University of Liege

Status: Completed

Conditions: Acute Kidney Injury After Adult Cardiac Surgery

Treatments: Drug: Crystalloid; Drug: HES

Study type: Observational

Funder types: Other

Identifiers

NCT02445820

ANES2015002

Details and patient eligibility

About

This study retrospectively assess the effect or using balanced hydroxyethyl sctarch (HES) 130/0.4 or a balanced crystalloid solution as a pump prime and for intraoperative fluid therapy on the risk of early acute postoperative kidney injury in adult cardiac surgery patients.

Enrollment: 697 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 18 yo
• Having on pump cardiac surgery at CHU of Liège between April 2013 and June 2014

Exclusion criteria

• Off pump surgery
• Use of Blood or Albumin in the cardiopulmonary bypass priming solution
• Preoperative dialysis

Trial design

697 participants in 2 patient groups

HES

Description:

Balanced HES 130/0.4 used as and pump prime and for intraoperative fluid therapy.

Treatment:

Drug: HES

Crystalloid

Description:

Balanced Crystalloid used as a pump prime and for intraoperative fluid therapy.

Treatment:

Drug: Crystalloid