HFNC and Prone Positioning in Awake Patients With Severe COVID-19

Hôpital Universitaire Fattouma Bourguiba

Status: Completed

Conditions: Hypoxemic Respiratory Failure

Treatments: Procedure: prone position

Study type: Observational

Funder types: Other

Identifiers

NCT04982341

FattoumaBourguiba_HFNC_Prone

Details and patient eligibility

About

The investigators evaluate the effects of High-flow nasal cannula (HFNC) in association with prone in patients with Covid-19 severe ARF.

Full description

The investigators evaluate the effects of High-flow nasal cannula (HFNC) in association with prone in patients with Covid-19 severe ARF.

All patients with ARF related to Covid-19 and admitted to the ICU are turned in prone position whenever tolerated, while receiving oxygenation with HFNC.

Outcomes of interest are the rate of success or failure (defined as the need for intubation and mechanical ventilation)

Enrollment: 120 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• aged ≥18 years, admitted to the medical ICU for confirmed Covid-19 and acute hypoxemic respiratory failure

Exclusion criteria

• patients already intubated at admission or those requiring immediate intubation

Trial design

120 participants in 1 patient group

HFNC/prone

Description:

awake patients with COVID-19 and severe acute respiratory failure receiving HFNC in prone position

Treatment:

Procedure: prone position