HFpEF and 2-year Mortality of COPD Patients (THERESE)

University Hospital Olomouc

Status: Enrolling

Conditions: Chronic Obstructive Pulmonary Disease; Heart Failure

Treatments: Diagnostic Test: Cardiac function assessment

Study type: Observational

Funder types: Other

Identifiers

NCT04277429

THERESE

Details and patient eligibility

About

This study was designed to assess potential relationship between heart failure with preserved ejection fraction and 2- year mortality of patients with chronic obstructive pulmonary disease

Enrollment: 150 estimated patients

Sex: All

Ages: 40 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Exacerbation of chronic obstructive pulmonary disease requiring hospitalization

Age 40 - 80 years

Performance status 0-1 according to Eastern Cooperative Oncology Group (ECOG)

Long acting beta agonist (LABA)/ long acting antimuscarinic (LAMA) bronchodilator treatment

Exclusion criteria

Presence of major heart valve dysfunction

Documented noncompliance with treatment

Presence of active malignancy

Body mass index > 40

Interstitial lung disease

Trial design

150 participants in 3 patient groups

Normal cardiac function

Description:

Normal cardiac function

Treatment:

Diagnostic Test: Cardiac function assessment

Heart failure with reduced ejection fraction

Description:

Heart failure with reduced ejection fraction

Treatment:

Diagnostic Test: Cardiac function assessment

Heart failure with preserved ejection fraction

Description:

Heart failure with preserved ejection fraction

Treatment:

Diagnostic Test: Cardiac function assessment