Hibiscus Sabdariffa and Centella Asiatica in the Treatment of Anemia by Iron Deficiency

Casa Espirita Terra de Ismael

Status and phase: Completed; Phase 3

Conditions: Iron Deficiency Anemia

Treatments: Drug: Herbal medicine; Drug: Iron

Study type: Interventional

Funder types: Other

Identifiers

NCT01414374

ANEMIA2011

Details and patient eligibility

About

The study aims to investigate the prevalence of genetic polymorphisms in adults with iron deficiency and anemia, and the responses to two different treatments: iron sulphate and a composite herbal medicine (Hibiscus sabdariffa plus Centella asiatica). The main outcome will be hemoglobin, measured before and after 6 weeks.

Enrollment: 50 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age > 18 y and < 50 y
• A diagnostic of iron deficient anemia

Exclusion criteria

• Severe anemia
• Treatment interruption for more than 25% of the 6 weeks
• New onset severe adverse symptoms or events
• Patient's request

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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50 participants in 2 patient groups

Iron

Active Comparator group

Treatment:

Drug: Iron

Herbal

Experimental group

Treatment:

Drug: Herbal medicine