Hidradenitis Suppurativa Wound Care

Wake Forest University (WFU)

Status and phase: Active, not recruiting; Phase 2

Conditions: Hidradenitis Suppurativa (HS)

Treatments: Combination Product: methylene blue, gentian violet, and ovine forestomach wound dressings

Study type: Interventional

Funder types: Other

Identifiers

NCT04354012

IRB00063673

Details and patient eligibility

About

The objective of this case series is to monitor time and outcome of healing of wounds associated with HS using Endoform [ovine forestomach], Hydrofera Blue [methylene blue and gentian violet], and Hypafix tape. a combination methylene blue, gentian violet, and ovine forestomach wound care product.

Full description

Hidradenitis suppurativa (HS) is a chronic and debilitating inflammatory disease most frequently affecting the axilla, groin, and inframammary regions. Symptoms include nodules, abscesses, sinus tract formation, malodorous drainage, and scarring. These symptoms interfere with everyday activities, which can lead to social embarrassment and isolation. Patients with HS suffer psychological effects, such as increased levels of anxiety, depression, and loneliness, which impair quality of life.

Patients suffer with the burden of at home wound care for recurrent, draining nodules. Persistent lesions affect patients' lives by limiting their daily activities. Currently, patients are instructed to use gauze and tape to cover draining wounds, but this can be insufficient and difficult due to the nature and location of lesions associated with HS. Patients suffer with caring for their wounds, which can lead to frustration. Providing patients with a standard wound care regimen to take home can improve patients' quality of life and control of their disease. General recommendations for wound care in HS patients are limited. Improvements in the standard of care for wound management in HS are needed to aid patients.

Enrollment: 5 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Individuals with hidradenitis suppurativa with non-healing wounds or draining abscesses/nodules
• Individuals over 18 years of age

Exclusion criteria

• Individuals younger than 18 years of age
• Individuals without a diagnosis of HS

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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5 participants in 1 patient group

Treatment

Experimental group

Description:

methylene blue, gentian violet, and ovine forestomach wound dressings to HS lesions

Treatment:

Combination Product: methylene blue, gentian violet, and ovine forestomach wound dressings