HIF-1 Alpha, VEGF and MMP-8 Levels in PICF of Smokers Versus Non Smokers

Future University in Egypt

Status: Completed

Conditions: Peri-Implantitis

Study type: Observational

Funder types: Other

Identifiers

NCT05325918

FUE13

Details and patient eligibility

About

Smoking is a major risk factor for developing peri-implantitis so the current study is comparing inflammatory markers in smokers versus non smokers to know if they have a potential role in pathogenesis of peri-implantitis

Full description

Peri -implant crevicular fluid was obtained from seven smoker patients and then compared to peri-implant crevicular fluid from seven non smoker individuals.

The peri-implant crevicular fluid was obtained using periopaper strips then analyzed using ELISA kits of these markers; HIF-1 Alpha, VEGF and MMP-8

Enrollment: 14 patients

Sex: All

Ages: 20 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Medically free patients
• Individuals with restored implants placed one year or more before study enrollment
• Both genders
• Age range 20-50 years old

Exclusion criteria

• Pregnant Females
• Lactating females