HIF-1 Alpha, VEGF and MMP-8 Levels in PICF of Smokers Versus Non Smokers

F

Future University in Egypt

Status

Completed

Conditions

Peri-Implantitis

Study type

Observational

Funder types

Other

Identifiers

NCT05325918
FUE13

Details and patient eligibility

About

Smoking is a major risk factor for developing peri-implantitis so the current study is comparing inflammatory markers in smokers versus non smokers to know if they have a potential role in pathogenesis of peri-implantitis

Full description

Peri -implant crevicular fluid was obtained from seven smoker patients and then compared to peri-implant crevicular fluid from seven non smoker individuals. The peri-implant crevicular fluid was obtained using periopaper strips then analyzed using ELISA kits of these markers; HIF-1 Alpha, VEGF and MMP-8

Enrollment

14 patients

Sex

All

Ages

20 to 50 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Medically free patients
  • Individuals with restored implants placed one year or more before study enrollment
  • Both genders
  • Age range 20-50 years old

Exclusion criteria

  • Pregnant Females
  • Lactating females

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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