High-definition Transcranial Direct Current Stimulation (HD-tDCS) Verbal Learning

The University of New South Wales

Status and phase: Completed; Early Phase 1

Conditions: Verbal Learning and Memory

Treatments: Device: HD-tDCS

Study type: Interventional

Funder types: Other

Identifiers

NCT01733576

CB64

Details and patient eligibility

About

This project will use a new form of non-invasive brain stimulation called high-definition transcranial direct current stimulation (HD-tDCS) to facilitate verbal learning. This form of stimulation is similar to transcranial direct current stimulation (tDCS) but allows for more spatially focused stimulation. We hypothesise that HD-tDCS when applied to regions of the brain important for learning and memory will improve verbal learning and memory compared to sham HD-tDCS.

Enrollment: 16 patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Ages 18 - 40 years
• Right-handed

Exclusion criteria

• concurrent medication likely to affect mental performance
• current history of drug or alcohol abuse or dependence
• any psychiatric or neurological disorder, recent head injury, or history of seizure or stroke.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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16 participants in 4 patient groups

Sham HD-tDCS

Sham Comparator group

Treatment:

Device: HD-tDCS

Active HD-tDCS 1

Active Comparator group

Treatment:

Device: HD-tDCS

Active HD-tDCS 2

Active Comparator group

Treatment:

Device: HD-tDCS

Active HD-tDCS 3

Active Comparator group

Treatment:

Device: HD-tDCS