High-density EEG in Neurological Disorders

Dartmouth Health

Status: Invitation-only

Conditions: Healthy; Epilepsy; Tumor

Treatments: Diagnostic Test: High-density electroencephalogram (HD-EEG)

Study type: Interventional

Funder types: Other

Identifiers

NCT04266041

D18111 30813

Details and patient eligibility

About

The purpose of the study is to use a new method of high-density electroencephalogram (HD-EEG) recording to map brain areas important for movement, sensation, language, emotion, and cognition.

Full description

This study will measure brain waves using high-density EEG. Participants will be asked wear a cap with electrodes attached to it. During the recording, participants may be asked to rest, sleep, or complete a task. The tasks involve viewing pictures, answering questions, speaking, or moving an arm or leg. Recordings generally last between 60-120 minutes.*

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Able to perform the tasks
• Able to give own consent

Exclusion criteria

• Any neurologic or psychiatric diagnosis such as stroke, tumor, or psychosis judged to interfere with high-density EEG.

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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100 participants in 5 patient groups

High-density EEG localization in epilepsy

Experimental group

Description:

High-density EEG will be used for brain localization in epilepsy patients

Treatment:

Diagnostic Test: High-density electroencephalogram (HD-EEG)

High-density EEG localization in healthy controls

Active Comparator group

Description:

High-density EEG will be used for brain localization in healthy controls

Treatment:

Diagnostic Test: High-density electroencephalogram (HD-EEG)

High-density EEG localization in tumor patients

Experimental group

Description:

High-density EEG will be used for brain localization in tumor patients

Treatment:

Diagnostic Test: High-density electroencephalogram (HD-EEG)

High-density EEG localization in peripheral nerve patients

Experimental group

Description:

High-density EEG will be used for brain localization in patients with peripheral nerve dysfunction

Treatment:

Diagnostic Test: High-density electroencephalogram (HD-EEG)

High-density EEG localization in stroke patients

Experimental group

Description:

High-density EEG will be used for brain localization in patients who have recently experienced a stroke

Treatment:

Diagnostic Test: High-density electroencephalogram (HD-EEG)